Category:Classes

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Classes in PRGDB

  Description
CN Contains coiled-coil and NBS domains
CNL Contains a central nucleotide-binding (NB) subdomain as part of a larger entity called the NB-ARC domain. C-terminal to the NB-ARC domain lies a leucine-rich repeat (LRR) domain, which is sometimes followed by an extension of variable length. Hence, this group of R proteins is collectively referred to as NB-LRR proteins. If N-terminal region contain a predicted coiled-coil structures (CC), non-TIR NB-LRR proteins are collectively referred to as CC-NB-LRR or CNL.
Kinase Kinase domain involved in resistance process
Mlo-like Mlo-like resistant proteins
N Contains NBS domain only, lack of LRR
NL Contains NBS domain at N-terminal and LRR st the C-terminal, and lack of the CC domain
Other The class “Other” consists in a miscellaneus set of R proteins that do not fit into any of the known four classes, but that has resistance function. To date 13 genes were cloned to that class indicating that there are other way to produce resistance in plant kingdom.
Pto-like Pto-like resistant proteins
RLK RLKs, or Receptor like Kinases, consist of an extracellullar leucine-rich repeat region (eLRR) that consist of 25-38aa conferring broad interaction surface that is well suited to interact with multiple ligands and an intracellular kinase domain. The eLRR domain plays the recognising role while the kinase triggers the downstream activation cascades. In Arabidopsis genome RLKs constitute a large gene family divided in 44 subclasses, 12 of them have the extracellular domain LRR while the other use different type of receptor like B-lactin and many others.
RLK-GNK2 RLK class with additional domain GNK2
RLP Receptor Like Proteins consists of a leucine-rich receptor-like repeat, a transmembrane region of ~25 AA, and a short cytoplasmic region, with no kinase domain. The extracellular leucine rich repeat (eLRR) shows high homology with the RLKs eLRR. RLPs can recognise avirulence genes in a indirect way like Cf2 that recognise the avirulence gene Avr2 through the cysteine protease Rcr3. There are also some hypotheses about a direct recognition, but this has not yet been demonstrated. RLPs lack an obvious signalling domain, suggesting that defence response activation is mediated through interactions with other partner proteins. Activation of RLP typically results in a rapid accumulation of active oxygen species (AOS), changes in cellular ion fluxes, activation of protein kinase cascades, changes in gene expression and, possibly, targeted protein degradation.
RPW8-NL Contains NBS ,LRR and RPW8 domains
T Contains TIR domain only, lack of LRR or NBS
TN Contains TIR and NBS domains
TNL Contains a central nucleotide-binding (NB) subdomain as part of a larger entity called the NB-ARC domain. C-terminal to the NB-ARC domain lies a leucine-rich repeat (LRR) domain, which is sometimes followed by an extension of variable length. Hence, this group of R proteins is collectively referred to as NB-LRR proteins. If N-terminal region shows homology to the protein domain Interleukin-1 Receptor (IL-1R), called the TIR domain, these proteins are referred to as TIR-NB-LRR or TNL.
Unknown Contains genes which might be resistant genes, but didn't fit in any other class.

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Pages in category "Classes"

The following 16 pages are in this category, out of 16 total.

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