PRGDB00000031 (Bs4)

Bs4
Gene Type	Reference_R-Genes,_manually_curated
GenBank	38489218 (AY438027)
Gene Class	TNL
Domain Type	LRR, NBS, LRR, TIR, Others
Chromosome	5
Gene Species	Solanum lycopersicum
	Comment?

Lycopersicon esculentum bacterial spot disease resistance protein 4 (Bs4) gene, Bs4-MM allele, complete cds.

DNA Sequence

ATGGCATCTTCTTCTTCTTCTTCTGCAAGTAATTCAAAGTATTATCCTCGATGGAAGTACGTTGTTTTTCTAAGTTTCAGAGGTGAAGACACTCGAAAAACATTTACAGGTCACTTATACGAAGGTTTGAGAAATAGAGGAATAAACACATTTCAAGATGATAAAAGACTAGAGCATGGAGATTCAATTCCAAAAGAACTCTTGAGAGCTATAGAAGATTCTCAAGTTGCACTTATCATTTTCTCAAAGAATTATGCTACATCTAGGTGGTGCTTGAATGAACTAGTGAAGATCATGGAATGCAAAGAGGAAGAAAATGGACAAACAGTCATACCGATCTTTTATAATGTGGATCCATCACATGTTCGATACCAAACTGAAAGCTTTGGAGCAGCATTTGCCAAACACGAATCAAAGTATAAGGATGATGTTGAGGGGATGCAGAAGGTGCAAAGATGGAGAACTGCCCTAACTGCTGCCGCAAATCTAAAAGGATATGATATCCGTAACGGGATTGAATCAGAGAATATTCAGCAGATCGTAGATTGCATCTCTTCCAAATTTTGTACGAATGCTTATTCTTTATCTTTTTTGCAAGATATTGTGGGAATAAATGCTCACTTAGAGAAACTAAAATCGAAACTTCAAATAGAAATCAATGATGTTCGGATTTTAGGGATCTGGGGAATAGGCGGAGTCGGTAAAACAAGAATAGCAAAAGCCATTTTTGATACTCTATCTTATCAATTTGAAGCTTCTTGTTTTCTTGCTGATGTTAAAGAATTTGCAAAAAAGAATAAACTGCATTCTTTACAAAATATTCTTCTCTCTGAACTGTTAAGGAAAAAAAATGATTACGTCTACAACAAGTATGATGGAAAGTGTATGATTCCAAACAGACTTTGTTCTTTGAAGGTTCTAATTGTGCTTGATGATATAGATCATGGTGATCAGATGGAGTATTTAGCAGGTGATATTTGTTGGTTTGGTAATGGCAGCAGAGTTATTGTAACAACTAGAAACAAACATTTGATAGAGAAAGATGATGCGATATACGAAGTGTCTACACTGCCTGATCATGAAGCTATGCAATTATTCAATATGCATGCTTTTAAAAAAGAAGTTCCAAATGAGGATTTTAAGGAGTTGGCGTTAGAGATAGTAAATCACGCTAAAGGCCTCCCTTTAGCCCTCAAGGTGTGGGGCTGTTTATTGCATAAAAAAAATCTCTCTTTATGGAAAATAACAGTAGAGCAAATAAAGAAAGACTCTAATTCAGAAATTGTTGAACAACTCAAAATAAGTTATGATGGGTTGGAGTCCGAAGAGCAGGAAATATTTTTAGATATAGCATGTTTCTTCCGCGGAGAGAAAAGAAAAGAGGTCATGCAAATTCTTAAGAGTTGTGACTTTGGAGCTGAATACGGATTGGATGTTCTGATTAATAAATCTCTTGTGTTCATATCTGAAAATGACAGGATTGAAATGCATGATTTGATTAGAGATATGGGTAGATATGTGGTGAAAATGCAAAAGCTTCAGAAAAAACGTAGCAGAATATGGGATGTTGAAGATTTCAAAGAAGTGATGATAGACTATACGGGGACCATGACAGTGGAAGCAATCTGGTTTAGTTGCTTTGAAGAAGTACGTTTTAATAAGGAGGCAATGAAAAAAATGAAAAGGCTTAGGATATTACACATATTTGATGGTTTTGTCAAATTCTTCTCTTCGCCTCCCTCTTCCAATTCCAATGATTCAGAAGAAGAAGATGATTCCTACGACTTAGTCGTAGATCACCATGATGACTCTATTGAGTACCTGTCCAATAACTTGCGTTGGTTAGTCTGGAATCACTATTCTTGGAAGTCATTGCCAGAAAATTTTAAACCAGAAAAGCTTGTTCATCTTGAACTCCGTTGGAGTTCGCTTCATTATTTATGGAAGAAAACAGAGCATTTGCCGTCTCTACGAAAGCTAGATCTCAGCTTATCTAAAAGTCTGGTGCAAACACCAGATTTCACGGGGATGCCAAATTTGGAGTATTTGAATCTGGAGTACTGTAGTAAGCTTGAAGAGGTTCACTATTCCCTAGCATATTGCGAAAAACTCATTGAGTTAAATTTGAGTTGGTGTACAAAGCTTAGGAGATTTCCATATATTAACATGGAATCTCTTGAATCTCTGGATCTACAATATTGCTATGGTATAATGGTGTTTCCAGAAATCATCGGAACGATGAAGCCGGAGTTAATGATTCTCTCAGCAAACACTATGATAACTGAACTACCATCATCTCTTCAGTACCCAACTCATCTCACAGAGCTAGATTTGAGTGGCATGGAAAACCTTGAAGCTCTTCCAAGCAGCATTGTCAAGTTGAAAGATTTGGTGAAGCTAAATGTGTCGTACTGCTTAACGCTTAAAAGCTTGCCTGAAGAGATTGGTGATTTAGAAAACTTGGAGGAACTTGATGCTTCGCGTACTCTAATTTCACAGCCTCCATCTTCCATTGTCCGCTTGAACAAGCTTAAATCCTTGAAGTTAATGAAACGAAACACATTAACAGATGATGTGTGCTTTGTGTTTCCTCCTGTGAATAACGGGTTACTCTCATTGGAAATTCTGGAGCTCGGTTCCTCCAATTTCGAAGATGGAAGAATTCCGGAAGATATTGGATGTTTATCCTCTTTGAAAGAGTTACGTCTCGAGGGAGATAATTTCAATCATTTGCCTCAAAGCATAGCCCAACTTGGTGCACTTCGATTCTTATACATAAAAGATTGCAGGAGTCTTACAAGTCTGCCAGAATTTCCACCGCAATTAGATACAATATTTGCAGATTGGAGCAATGATTTGATCTGTAAGTCACTGTTTCTAAATATCTCATCATTCCAACATAACATCTCTGCTTCAGATTCGTTGTCGTTAAGAGTGTTTACGAGTTTGGGGAGTAGTATCCCAATCTGGTTCCACCATCAGGGAACAGATACAAGTGTTTCAGTCAATTTGCCTGAAAACTGGTATGTATCAGATAACTTCTTGGGATTCGCTGTATGTTACTATGGCAATTTAACTGAGAACACAGCTGAATTGATTATGAGTTCTGCAGGGATGCCATGTATCACCTGGAAACTTTTGTTATCGAATCATTCAGAATGTACATATATTAGGATTCATTTTTTCTTGGTACCTTTTGCTGGCTTATGGGATACATCTAACGCCAATGGTAAAACACCAAATGACTATAAGCACATTATGTTATCTTTTCCTCAAGAATTGAAGGAGTGTGGAGTTCGTTTGTTCTATGAAGATGAATCTGTGCTTGAGACCACCAATGATGAACTTACCATTGGGGTAAGGAGGATCAGATACGACGACGACGATAGTGAACATTATGAGGAGGCTGGTTGTTCCTCTTCTAAGAAACAAAGATCATAA

Protein sequences

Name	Description	Sequence
bacterial spot disease resistance protein 4	bacterial spot disease resistance protein 4 [Lycopersicon esculentum].	MASSSSSSASNSKYYPRWKYVVFLSFRGEDTRKTFTGHLYEGLRNRGINTFQDDKRLEHGDSIPKELLRAIEDSQVALIIFSKNYATSRWCLNELVKIMECKEEENGQTVIPIFYNVDPSHVRYQTESFGAAFAKHESKYKDDVEGMQKVQRWRTALTAAANLKGYDIRNGIESENIQQIVDCISSKFCTNAYSLSFLQDIVGINAHLEKLKSKLQIEINDVRILGIWGIGGVGKTRIAKAIFDTLSYQFEASCFLADVKEFAKKNKLHSLQNILLSELLRKKNDYVYNKYDGKCMIPNRLCSLKVLIVLDDIDHGDQMEYLAGDICWFGNGSRVIVTTRNKHLIEKDDAIYEVSTLPDHEAMQLFNMHAFKKEVPNEDFKELALEIVNHAKGLPLALKVWGCLLHKKNLSLWKITVEQIKKDSNSEIVEQLKISYDGLESEEQEIFLDIACFFRGEKRKEVMQILKSCDFGAEYGLDVLINKSLVFISENDRIEMHDLIRDMGRYVVKMQKLQKKRSRIWDVEDFKEVMIDYTGTMTVEAIWFSCFEEVRFNKEAMKKMKRLRILHIFDGFVKFFSSPPSSNSNDSEEEDDSYDLVVDHHDDSIEYLSNNLRWLVWNHYSWKSLPENFKPEKLVHLELRWSSLHYLWKKTEHLPSLRKLDLSLSKSLVQTPDFTGMPNLEYLNLEYCSKLEEVHYSLAYCEKLIELNLSWCTKLRRFPYINMESLESLDLQYCYGIMVFPEIIGTMKPELMILSANTMITELPSSLQYPTHLTELDLSGMENLEALPSSIVKLKDLVKLNVSYCLTLKSLPEEIGDLENLEELDASRTLISQPPSSIVRLNKLKSLKLMKRNTLTDDVCFVFPPVNNGLLSLEILELGSSNFEDGRIPEDIGCLSSLKELRLEGDNFNHLPQSIAQLGALRFLYIKDCRSLTSLPEFPPQLDTIFADWSNDLICKSLFLNISSFQHNISASDSLSLRVFTSLGSSIPIWFHHQGTDTSVSVNLPENWYVSDNFLGFAVCYYGNLTENTAELIMSSAGMPCITWKLLLSNHSECTYIRIHFFLVPFAGLWDTSNANGKTPNDYKHIMLSFPQELKECGVRLFYEDESVLETTNDELTIGVRRIRYDDDDSEHYEEAGCSSSKKQRS

Domains

Domain	Start-End	Description	Sequence
superfamily: SSF52200 IPR000157	8-166	TIR Toll/interleukin-1 receptor homology (TIR) domain	SASNSKYYPRWKYVVFLSFRGEDTRKTFTGHLYEGLRNRGINTFQDDKRLEHGDSIPKELLRAIEDSQVALIIFSKNYATSRWCLNELVKIMECKEEENGQTVIPIFYNVDPSHVRYQTESFGAAFAKHESKYKDDVEGMQKVQRWRTALTAAANLKGY
Gene3D: G3DSA:3.40.50.10140	17-156	G3DSA:3.40.50.10140	RWKYVVFLSFRGEDTRKTFTGHLYEGLRNRGINTFQDDKRLEHGDSIPKELLRAIEDSQVALIIFSKNYATSRWCLNELVKIMECKEEENGQTVIPIFYNVDPSHVRYQTESFGAAFAKHESKYKDDVEGMQKVQRWRTA
ProfileScan: PS50104 IPR000157	18-163	TIR Toll/interleukin-1 receptor homology (TIR) domain	WKYVVFLSFRGEDTRKTFTGHLYEGLRNRGINTFQDDKRLEHGDSIPKELLRAIEDSQVALIIFSKNYATSRWCLNELVKIMECKEEENGQTVIPIFYNVDPSHVRYQTESFGAAFAKHESKYKDDVEGMQKVQRWRTALTAAANL
HMMSmart: SM00255 IPR000157	19-163	TIR Toll/interleukin-1 receptor homology (TIR) domain	KYVVFLSFRGEDTRKTFTGHLYEGLRNRGINTFQDDKRLEHGDSIPKELLRAIEDSQVALIIFSKNYATSRWCLNELVKIMECKEEENGQTVIPIFYNVDPSHVRYQTESFGAAFAKHESKYKDDVEGMQKVQRWRTALTAAANL
HMMPfam: PF01582 IPR000157	22-158	TIR Toll/interleukin-1 receptor homology (TIR) domain	VFLSFRGEDTRKTFTGHLYEGLRNRGINTFQDDKRLEHGDSIPKELLRAIEDSQVALIIFSKNYATSRWCLNELVKIMECKEEENGQTVIPIFYNVDPSHVRYQTESFGAAFAKHESKYKDDVEGMQKVQRWRTALT
HMMPanther: PTHR11017	50-958	PTHR11017,LEUCINE-RICH REPEAT-CONTAINING PROTEIN	TFQDDKRLEHGDSIPKELLRAIEDSQVALIIFSKNYATSRWCLNELVKIMECKEEENGQTVIPIFYNVDPSHVRYQTESFGAAFAKHESKYKDDVEGMQKVQRWRTALTAAANLKGYDIRNGIESENIQQIVDCISSKFCTNAYSLSFLQDIVGINAHLEKLKSKLQIEINDVRILGIWGIGGVGKTRIAKAIFDTLSYQFEASCFLADVKEFAKKNKLHSLQNILLSELLRKKNDYVYNKYDGKCMIPNRLCSLKVLIVLDDIDHGDQMEYLAGDICWFGNGSRVIVTTRNKHLIEKDDAIYEVSTLPDHEAMQLFNMHAFKKEVPNEDFKELALEIVNHAKGLPLALKVWGCLLHKKNLSLWKITVEQIKKDSNSEIVEQLKISYDGLESEEQEIFLDIACFFRGEKRKEVMQILKSCDFGAEYGLDVLINKSLVFISENDRIEMHDLIRDMGRYVVKMQKLQKKRSRIWDVEDFKEVMIDYTGTMTVEAIWFSCFEEVRFNKEAMKKMKRLRILHIFDGFVKFFSSPPSSNSNDSEEEDDSYDLVVDHHDDSIEYLSNNLRWLVWNHYSWKSLPENFKPEKLVHLELRWSSLHYLWKKTEHLPSLRKLDLSLSKSLVQTPDFTGMPNLEYLNLEYCSKLEEVHYSLAYCEKLIELNLSWCTKLRRFPYINMESLESLDLQYCYGIMVFPEIIGTMKPELMILSANTMITELPSSLQYPTHLTELDLSGMENLEALPSSIVKLKDLVKLNVSYCLTLKSLPEEIGDLENLEELDASRTLISQPPSSIVRLNKLKSLKLMKRNTLTDDVCFVFPPVNNGLLSLEILELGSSNFEDGRIPEDIGCLSSLKELRLEGDNFNHLPQSIAQLGALRFLYIKDCRSLTSLPEFPPQLDTIFADWSNDLICKSL
HMMPanther: PTHR11017:SF20	50-958	PTHR11017:SF20,SUBFAMILY NOT NAMED	TFQDDKRLEHGDSIPKELLRAIEDSQVALIIFSKNYATSRWCLNELVKIMECKEEENGQTVIPIFYNVDPSHVRYQTESFGAAFAKHESKYKDDVEGMQKVQRWRTALTAAANLKGYDIRNGIESENIQQIVDCISSKFCTNAYSLSFLQDIVGINAHLEKLKSKLQIEINDVRILGIWGIGGVGKTRIAKAIFDTLSYQFEASCFLADVKEFAKKNKLHSLQNILLSELLRKKNDYVYNKYDGKCMIPNRLCSLKVLIVLDDIDHGDQMEYLAGDICWFGNGSRVIVTTRNKHLIEKDDAIYEVSTLPDHEAMQLFNMHAFKKEVPNEDFKELALEIVNHAKGLPLALKVWGCLLHKKNLSLWKITVEQIKKDSNSEIVEQLKISYDGLESEEQEIFLDIACFFRGEKRKEVMQILKSCDFGAEYGLDVLINKSLVFISENDRIEMHDLIRDMGRYVVKMQKLQKKRSRIWDVEDFKEVMIDYTGTMTVEAIWFSCFEEVRFNKEAMKKMKRLRILHIFDGFVKFFSSPPSSNSNDSEEEDDSYDLVVDHHDDSIEYLSNNLRWLVWNHYSWKSLPENFKPEKLVHLELRWSSLHYLWKKTEHLPSLRKLDLSLSKSLVQTPDFTGMPNLEYLNLEYCSKLEEVHYSLAYCEKLIELNLSWCTKLRRFPYINMESLESLDLQYCYGIMVFPEIIGTMKPELMILSANTMITELPSSLQYPTHLTELDLSGMENLEALPSSIVKLKDLVKLNVSYCLTLKSLPEEIGDLENLEELDASRTLISQPPSSIVRLNKLKSLKLMKRNTLTDDVCFVFPPVNNGLLSLEILELGSSNFEDGRIPEDIGCLSSLKELRLEGDNFNHLPQSIAQLGALRFLYIKDCRSLTSLPEFPPQLDTIFADWSNDLICKSL
superfamily: SSF52540	181-428	SSF52540	VDCISSKFCTNAYSLSFLQDIVGINAHLEKLKSKLQIEINDVRILGIWGIGGVGKTRIAKAIFDTLSYQFEASCFLADVKEFAKKNKLHSLQNILLSELLRKKNDYVYNKYDGKCMIPNRLCSLKVLIVLDDIDHGDQMEYLAGDICWFGNGSRVIVTTRNKHLIEKDDAIYEVSTLPDHEAMQLFNMHAFKKEVPNEDFKELALEIVNHAKGLPLALKVWGCLLHKKNLSLWKITVEQIKKDSNSEI
Gene3D: G3DSA:3.40.50.300	199-347	G3DSA:3.40.50.300	QDIVGINAHLEKLKSKLQIEINDVRILGIWGIGGVGKTRIAKAIFDTLSYQFEASCFLADVKEFAKKNKLHSLQNILLSELLRKKNDYVYNKYDGKCMIPNRLCSLKVLIVLDDIDHGDQMEYLAGDICWFGNGSRVIVTTRNKHLIEK
HMMPfam: PF00931 IPR002182	205-469	NB-ARC,NBS NB-ARC	NAHLEKLKSKLQIEINDVRILGIWGIGGVGKTRIAKAIFDTLSYQFEASCFLADVKEFAKKNKLHSLQNILLSELLRKKNDYVYNKYDGKCMIPNRLCSLKVLIVLDDIDHGDQMEYLAGDICWFGNGSRVIVTTRNKHLIEKDDAIYEVSTLPDHEAMQLFNMHAFKKEVPNEDFKELALEIVNHAKGLPLALKVWGCLLHKKNLSLWKITVEQIKKDSNSEIVEQLKISYDGLESEEQEIFLDIACFFRGEKRKEVMQILKSC
FPrintScan: PR00364 IPR000767	224-239	DISEASERSIST Disease resistance protein	ILGIWGIGGVGKTRIA
FPrintScan: PR00364 IPR000767	300-314	DISEASERSIST Disease resistance protein	RLCSLKVLIVLDDID
FPrintScan: PR00364 IPR000767	391-405	DISEASERSIST Disease resistance protein	AKGLPLALKVWGCLL
superfamily: SSF46785	426-531	SSF46785	SEIVEQLKISYDGLESEEQEIFLDIACFFRGEKRKEVMQILKSCDFGAEYGLDVLINKSLVFISENDRIEMHDLIRDMGRYVVKMQKLQKKRSRIWDVEDFKEVMI
superfamily: SSF52058	495-973	SSF52058,LRR	EMHDLIRDMGRYVVKMQKLQKKRSRIWDVEDFKEVMIDYTGTMTVEAIWFSCFEEVRFNKEAMKKMKRLRILHIFDGFVKFFSSPPSSNSNDSEEEDDSYDLVVDHHDDSIEYLSNNLRWLVWNHYSWKSLPENFKPEKLVHLELRWSSLHYLWKKTEHLPSLRKLDLSLSKSLVQTPDFTGMPNLEYLNLEYCSKLEEVHYSLAYCEKLIELNLSWCTKLRRFPYINMESLESLDLQYCYGIMVFPEIIGTMKPELMILSANTMITELPSSLQYPTHLTELDLSGMENLEALPSSIVKLKDLVKLNVSYCLTLKSLPEEIGDLENLEELDASRTLISQPPSSIVRLNKLKSLKLMKRNTLTDDVCFVFPPVNNGLLSLEILELGSSNFEDGRIPEDIGCLSSLKELRLEGDNFNHLPQSIAQLGALRFLYIKDCRSLTSLPEFPPQLDTIFADWSNDLICKSLFLNISSFQHNISASD
Gene3D: G3DSA:3.80.10.10	608-851	G3DSA:3.80.10.10	LSNNLRWLVWNHYSWKSLPENFKPEKLVHLELRWSSLHYLWKKTEHLPSLRKLDLSLSKSLVQTPDFTGMPNLEYLNLEYCSKLEEVHYSLAYCEKLIELNLSWCTKLRRFPYINMESLESLDLQYCYGIMVFPEIIGTMKPELMILSANTMITELPSSLQYPTHLTELDLSGMENLEALPSSIVKLKDLVKLNVSYCLTLKSLPEEIGDLENLEELDASRTLISQPPSSIVRLNKLKSLKLMK
FPrintScan: PR00364 IPR000767	652-668	DISEASERSIST Disease resistance protein	EHLPSLRKLDLSLSKSL
Gene3D: G3DSA:3.80.10.10	864-940	G3DSA:3.80.10.10	PPVNNGLLSLEILELGSSNFEDGRIPEDIGCLSSLKELRLEGDNFNHLPQSIAQLGALRFLYIKDCRSLTSLPEFPP

Diseases

Disease	Pathogen	Avirulence gene
Bacterial Spot	Xanthomonas campestris	PRGAV00000030
Bacterial Spot	Xanthomonas campestris	PRGAV00000031

List of References

Sebastian Schornack, Agim Ballvora, Doreen Gürlebeck, Jack Peart, David Baulcombe, Martin Ganal, Barbara Baker, Ulla Bonas, Thomas Lahaye
The tomato resistance protein Bs4 is a predicted non-nuclear TIR-NB-LRR protein that mediates defense responses to severely truncated derivatives of AvrBs4 and overexpressed AvrBs3.
Plant J.: 2004, 37(1);46-60
PubMed:14675431 WorldCat.org (P p)

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Analyses

Blast

Blast matches against Reference R-Genes. Show