PRGDB00000033 (Cf-4)
| Cf-4 | |
|---|---|
| Gene Type | Reference_R-Genes,_manually_curated |
| GenBank | 2808679 (AJ002235) |
| Gene Class | RLP |
| Domain Type | LRR, LRR, Ser-Thr Kinase, Ser-Thr Kinase |
| Chromosome | 1 |
| Gene Species | Solanum habrochaites |
DNA Sequence
ATGGGTTGTGTAAAACTTGTGTTTTTCATGCTATATGTCTTTCTCTTTCAACTTGTTTCCTCGTCATCCTTACCTCATTTGTGCCCCGAAGATCAAGCTCTTGCTCTTCTAGAATTCAAGAACATGTTTACCGTTAATCCTAATGCTTCTGATTATTGTTACGACAGAAGAACTCTTTCTTGGAACAAAAGCACAAGTTGCTGCTCATGGGATGGCGTTCATTGTGACGAAACGACAGGACAAGTGATTGAGCTTGACCTCCGTTGCATCCAACTTCAAGGCAAGTTTCATTCCAATAGTAGCCTCTTTCAACTCTCCAATCTCAAAAGGCTTGATTTGTCTTATAATGATTTCACTGGATCGCCCATTTCACCTAAATTTGGTGAGTTTTCAGATTTGACGCATCTCGATTTGTCGCATTCAAGTTTTAGGGGTGTAATCCCTTCTGAAATCTCTCATCTTTCTAAACTATACGTTCTTCGTATTAGTCTAAATGAGCTTACTTTTGGTCCTCACAATTTTGAATTGCTTCTTAAGAACTTGACCCAATTAAAAGTGCTCGACCTTGAATCTATCAACATCTCTTCCACTATTCCTTTGAATTTCTCTTCTCATTTAACAAATCTATGGCTTCCATACACAGAGTTACGTGGGATATTGCCCGAAAGAGTTTTCCACCTTTCCGACTTAGAATTTCTCGATTTATCAAGCAATCCCCAGCTCACGGTTAGGTTTCCCACAACCAAATGGAATAGCAGTGCATCACTCATGAAGTTATATCTCTATAATGTGAATATTGATGATAGGATACCTGAATCATTTAGCCATCTAACTTCACTTCATAAGTTGTACATGAGTCGTTCTAATCTGTCAGGGCCTATTCCTAAACCTCTATGGAATCTCACCAACATAGTGTTTTTGGACCTTAATAATAACCATCTTGAAGGACCAATTCCATCCAACGTAAGCGGACTACGTAACCTACAAATACTTTGGTTGTCATCAAACAACTTAAATGGGAGTATACCATCCTGGATATTCTCCCTTCCATCACTGATAGGGTTAGACTTGAGCAATAACACTTTCAGTGGAAAAATTCAAGAGTTCAAGTCCAAAACATTAAGTACCGTTACTCTAAAACAAAATAAGCTAAAAGGTCCTATTCCGAATTCACTCCTAAACCAGAAGAACCTACAATTCCTTCTCCTTTCACACAATAATATCAGTGGACATATTTCTTCAGCTATCTGCAATCTGAAAACATTGATATTGTTAGACTTGGGAAGTAATAATTTGGAGGGAACAATCCCGCAATGCGTGGTTGAGAGGAACGAATACCTTTCGCATTTGGATTTGAGCAACAACAGACTTAGTGGGACAATCAATACAACTTTTAGTGTTGGAAACATTTTAAGGGTCATTAGCTTGCACGGGAATAAGCTAACGGGGAAAGTCCCACGATCTATGATCAATTGCAAGTATTTGACACTACTTGATCTAGGTAACAATATGTTGAATGACACATTTCCAAACTGGTTGGGATACCTATTTCAATTGAAGATTTTAAGCTTGAGATCAAATAAGTTGCATGGTCCCATCAAATCTTCAGGGAATACAAACTTGTTTATGGGTCTTCAAATTCTTGATCTATCATCTAATGGATTTAGTGGGAATTTACCCGAAAGAATTTTGGGGAATTTGCAAACCATGAAGGAAATTGATGAGAGTACAGGATTCCCAGAGTATATTTCTGATCCATATGATATTTATTACAATTATTTGACGACAATTTCTACAAAGGGACAAGATTATGATTCTGTTCGAATTTTGGATTCTAACATGATTATCAATCTCTCAAAGAACAGATTTGAAGGTCATATTCCAAGCATTATTGGAGATCTTGTTGGACTTCGTACGTTGAACTTGTCTCACAATGTCTTGGAAGGTCATATACCGGCATCATTTCAAAATTTATCAGTACTCGAATCATTGGATCTCTCATCTAATAAAATCAGCGGAGAAATTCCGCAGCAGCTTGCATCCCTCACATTCCTTGAAGTCTTAAATCTCTCTCACAATCATCTTGTTGGATGCATCCCCAAAGGAAAACAATTTGATTCGTTCGGGAACACTTCGTACCAAGGGAATGATGGGTTACGCGGATTTCCACTCTCAAAACTTTGTGGTGGTGAAGATCAAGTGACAACTCCAGCTGAGCTAGATCAAGAAGAGGAGGAAGAAGATTCACCAATGATCAGTTGGCAGGGGGTTCTCGTGGGTTACGGTTGTGGACTTGTTATTGGACTGTCCGTAATATACATAATGTGGTCAACTCAATATCCAGCATGGTTTTCGAGGATGGATTTAAAGTTGGAACACATAATTACTACGAAAATGAAAAAGCACAAGAAAAGATATTAG
Protein sequences
| Name | Description | Sequence |
|---|---|---|
| Cf-4 | Cf-4 [Solanum habrochaites]. | MGCVKLVFFMLYVFLFQLVSSSSLPHLCPEDQALALLEFKNMFTVNPNASDYCYDRRTLSWNKSTSCCSWDGVHCDETTGQVIELDLRCIQLQGKFHSNSSLFQLSNLKRLDLSYNDFTGSPISPKFGEFSDLTHLDLSHSSFRGVIPSEISHLSKLYVLRISLNELTFGPHNFELLLKNLTQLKVLDLESINISSTIPLNFSSHLTNLWLPYTELRGILPERVFHLSDLEFLDLSSNPQLTVRFPTTKWNSSASLMKLYLYNVNIDDRIPESFSHLTSLHKLYMSRSNLSGPIPKPLWNLTNIVFLDLNNNHLEGPIPSNVSGLRNLQILWLSSNNLNGSIPSWIFSLPSLIGLDLSNNTFSGKIQEFKSKTLSTVTLKQNKLKGPIPNSLLNQKNLQFLLLSHNNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSNNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPIKSSGNTNLFMGLQILDLSSNGFSGNLPERILGNLQTMKEIDESTGFPEYISDPYDIYYNYLTTISTKGQDYDSVRILDSNMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGNDGLRGFPLSKLCGGEDQVTTPAELDQEEEEEDSPMISWQGVLVGYGCGLVIGLSVIYIMWSTQYPAWFSRMDLKLEHIITTKMKKHKKRY |
Domains
| Domain | Start-End | Description | Sequence
|
|---|---|---|---|
| HMMPanther: PTHR24420:SF473 | 1-729 | PTHR24420:SF473,SUBFAMILY NOT NAMED | MGCVKLVFFMLYVFLFQLVSSSSLPHLCPEDQALALLEFKNMFTVNPNASDYCYDRRTLSWNKSTSCCSWDGVHCDETTGQVIELDLRCIQLQGKFHSNSSLFQLSNLKRLDLSYNDFTGSPISPKFGEFSDLTHLDLSHSSFRGVIPSEISHLSKLYVLRISLNELTFGPHNFELLLKNLTQLKVLDLESINISSTIPLNFSSHLTNLWLPYTELRGILPERVFHLSDLEFLDLSSNPQLTVRFPTTKWNSSASLMKLYLYNVNIDDRIPESFSHLTSLHKLYMSRSNLSGPIPKPLWNLTNIVFLDLNNNHLEGPIPSNVSGLRNLQILWLSSNNLNGSIPSWIFSLPSLIGLDLSNNTFSGKIQEFKSKTLSTVTLKQNKLKGPIPNSLLNQKNLQFLLLSHNNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSNNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPIKSSGNTNLFMGLQILDLSSNGFSGNLPERILGNLQTMKEIDESTGFPEYISDPYDIYYNYLTTISTKGQDYDSVRILDSNMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGNDGLRGFPLSKLCG |
| HMMPanther: PTHR24420 | 1-729 | PTHR24420,FAMILY NOT NAMED | MGCVKLVFFMLYVFLFQLVSSSSLPHLCPEDQALALLEFKNMFTVNPNASDYCYDRRTLSWNKSTSCCSWDGVHCDETTGQVIELDLRCIQLQGKFHSNSSLFQLSNLKRLDLSYNDFTGSPISPKFGEFSDLTHLDLSHSSFRGVIPSEISHLSKLYVLRISLNELTFGPHNFELLLKNLTQLKVLDLESINISSTIPLNFSSHLTNLWLPYTELRGILPERVFHLSDLEFLDLSSNPQLTVRFPTTKWNSSASLMKLYLYNVNIDDRIPESFSHLTSLHKLYMSRSNLSGPIPKPLWNLTNIVFLDLNNNHLEGPIPSNVSGLRNLQILWLSSNNLNGSIPSWIFSLPSLIGLDLSNNTFSGKIQEFKSKTLSTVTLKQNKLKGPIPNSLLNQKNLQFLLLSHNNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSNNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPIKSSGNTNLFMGLQILDLSSNGFSGNLPERILGNLQTMKEIDESTGFPEYISDPYDIYYNYLTTISTKGQDYDSVRILDSNMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGNDGLRGFPLSKLCG |
| Gene3D: G3DSA:3.80.10.10 | 28-248 | G3DSA:3.80.10.10 | CPEDQALALLEFKNMFTVNPNASDYCYDRRTLSWNKSTSCCSWDGVHCDETTGQVIELDLRCIQLQGKFHSNSSLFQLSNLKRLDLSYNDFTGSPISPKFGEFSDLTHLDLSHSSFRGVIPSEISHLSKLYVLRISLNELTFGPHNFELLLKNLTQLKVLDLESINISSTIPLNFSSHLTNLWLPYTELRGILPERVFHLSDLEFLDLSSNPQLTVRFPTT |
| HMMPfam: PF08263 IPR013210
|
30-76 | LRRNT_2 Leucine-rich repeat-containing N-terminal, type 2
|
EDQALALLEFKNMFTVNPNASDYCYDRRTLSWNKSTSCCSWDGVHCD |
| superfamily: SSF52047 | 84-409 | SSF52047,LRR | ELDLRCIQLQGKFHSNSSLFQLSNLKRLDLSYNDFTGSPISPKFGEFSDLTHLDLSHSSFRGVIPSEISHLSKLYVLRISLNELTFGPHNFELLLKNLTQLKVLDLESINISSTIPLNFSSHLTNLWLPYTELRGILPERVFHLSDLEFLDLSSNPQLTVRFPTTKWNSSASLMKLYLYNVNIDDRIPESFSHLTSLHKLYMSRSNLSGPIPKPLWNLTNIVFLDLNNNHLEGPIPSNVSGLRNLQILWLSSNNLNGSIPSWIFSLPSLIGLDLSNNTFSGKIQEFKSKTLSTVTLKQNKLKGPIPNSLLNQKNLQFLLLSHNNIS |
| HMMPfam: PF13516 | 105-119 | LRR_6,Leucine Rich repeat | LSNLKRLDLSYNDFT |
| ProfileScan: PS51450 IPR001611
|
107-128 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
NLKRLDLSYNDFTGSPISPKFG |
| HMMPfam: PF00560 IPR001611
|
133-154 | LRR_1 Leucine-rich repeat
|
LTHLDLSHSSFRGVIPSEISHL |
| ProfileScan: PS51450 IPR001611
|
156-177 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
KLYVLRISLNELTFGPHNFELL |
| ProfileScan: PS51450 IPR001611
|
183-204 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
QLKVLDLESINISSTIPLNFSS |
| Gene3D: G3DSA:3.80.10.10 | 251-455 | G3DSA:3.80.10.10 | NSSASLMKLYLYNVNIDDRIPESFSHLTSLHKLYMSRSNLSGPIPKPLWNLTNIVFLDLNNNHLEGPIPSNVSGLRNLQILWLSSNNLNGSIPSWIFSLPSLIGLDLSNNTFSGKIQEFKSKTLSTVTLKQNKLKGPIPNSLLNQKNLQFLLLSHNNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSNN |
| ProfileScan: PS51450 IPR001611
|
255-277 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
SLMKLYLYNVNIDDRIPESFSHL |
| ProfileScan: PS51450 IPR001611
|
303-326 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
NIVFLDLNNNHLEGPIPSNVSGLR |
| ProfileScan: PS51450 IPR001611
|
327-349 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
NLQILWLSSNNLNGSIPSWIFSL |
| HMMPfam: PF00560 IPR001611
|
327-348 | LRR_1 Leucine-rich repeat
|
NLQILWLSSNNLNGSIPSWIFS |
| ProfileScan: PS51450 IPR001611
|
351-373 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
SLIGLDLSNNTFSGKIQEFKSKT |
| superfamily: SSF52058 | 372-717 | SSF52058,LRR | KTLSTVTLKQNKLKGPIPNSLLNQKNLQFLLLSHNNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSNNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPIKSSGNTNLFMGLQILDLSSNGFSGNLPERILGNLQTMKEIDESTGFPEYISDPYDIYYNYLTTISTKGQDYDSVRILDSNMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGND |
| HMMPfam: PF13516 | 396-418 | LRR_6,Leucine Rich repeat | KNLQFLLLSHNNISGHISSAICN |
| ProfileScan: PS51450 IPR001611
|
397-420 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
NLQFLLLSHNNISGHISSAICNLK |
| ProfileScan: PS51450 IPR001611
|
446-467 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
YLSHLDLSNNRLSGTINTTFSV |
| HMMPfam: PF13855 | 446-505 | LRR_8,Leucine rich repeat | YLSHLDLSNNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNML |
| FPrintScan: PR00019 | 447-460 | LEURICHRPT,Leucine-rich repeat signature | LSHLDLSNNRLSGT |
| Gene3D: G3DSA:3.80.10.10 | 456-572 | G3DSA:3.80.10.10 | RLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPIKSSGNTNLFMGLQILDLSSNGFSGNLPERILGNLQTMKE |
| ProfileScan: PS51450 IPR001611
|
494-516 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
YLTLLDLGNNMLNDTFPNWLGYL |
| ProfileScan: PS51450 IPR001611
|
518-539 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
QLKILSLRSNKLHGPIKSSGNT |
| ProfileScan: PS51450 IPR001611
|
544-565 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
GLQILDLSSNGFSGNLPERILG |
| HMMPfam: PF00560 IPR001611
|
545-567 | LRR_1 Leucine-rich repeat
|
LQILDLSSNGFSGNLPERILGNL |
| Gene3D: G3DSA:3.80.10.10 | 616-726 | G3DSA:3.80.10.10 | INLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGNDGLRGFPLSK |
| HMMPfam: PF13855 | 636-695 | LRR_8,Leucine rich repeat | GLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHL |
| ProfileScan: PS51450 IPR001611
|
636-659 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
GLRTLNLSHNVLEGHIPASFQNLS |
| ProfileScan: PS51450 IPR001611
|
660-683 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
VLESLDLSSNKISGEIPQQLASLT |
| FPrintScan: PR00019 | 682-695 | LEURICHRPT,Leucine-rich repeat signature | LTFLEVLNLSHNHL |
| ProfileScan: PS51450 IPR001611
|
684-706 | LRR,Leucine-rich repeat profile. Leucine-rich repeat
|
FLEVLNLSHNHLVGCIPKGKQFD |
Diseases
| Disease | Pathogen | Avirulence gene |
|---|---|---|
| Leaf Mould | Passalora fulva | PRGAV00000033 |
List of References
M Parniske, K E Hammond-Kosack, C Golstein, C M Thomas, D A Jones, K Harrison, B B Wulff, J D Jones
Novel disease resistance specificities result from sequence exchange between tandemly repeated genes at the Cf-4/9 locus of tomato.
Cell: 1997, 91(6);821-32
PubMed:9413991
WorldCat.org
(P p)
List of Contributions
There has not been any contribution yet.
