PRGDB00000482 (At2)

At2
Gene Type	Reference_R-Genes,_manually_curated
GenBank	18158220 (AF461048)
Gene Class	Other
Domain Type	Ser-Thr Kinase
Gene Species	Cucumis melo
	Comment?

Cucumis melo aminotransferase 2 mRNA, complete cds.

DNA Sequence

ATGGACTATGTTTATGGACCTGGAAGGAACCATCTTTTTGTGCCGGGGCCGGTTAATATCCCCGAACAAGTCCTTCGAGCAATGAACCGGAACAACGAGGATTATCGTTCTCCAGCTGTTCCAGCACTGACAAAGACTCTGCTTGAGGATGTCAAAAAGATATTCAAAACCACATCAGGCACTCCATTTTTGTTCCCTACCACAGGTACTGGTGCATGGGAGAGTGCTCTCACAAACACATTGTCTCCGGGAGATCGGATCGTGTCATTCCTTATTGGTCAATTCAGTTTGCTTTGGATTGATCAGCAACAGCGTCTCAATTTCAAAGTCGACGTGATTGAAAGTGAATGGGGTGAAGGTGCTAAGCTTGATGTTTTAGCTGCAAAGCTTGCAGCTGATACTGATCATACTATAAAGGCAGTTTGCATTGTTCATAATGAGACAGCAACTGGCGTGACTAATGATTTGTCTCTAGTAAGAAGAATACTACATGAATACAGGCATCCAGCTCTTTTCCTCGTGGATGGAGTGTCTTCGATATGTGCTCTTGATTTTCGTATGGATGATTGGGGAGTGGATGTGGCTTTAACTGGCTCTCAAAAAGCTCTTTCCCTTCCCACCGGAATTGGTATTGTTTGCGCCAGCCCCCGAGCACTCGAGGCATCTAAAACAGCAAAATCACTCAGAGTTTTCTTTGACTGGAAGGACTATCTCAAGTTCTATAACTTAGGAACATACTGGCCTTACACTCCTTCCATCCAACTCTTATATGGGCTTAGACCAGCTTTGGACCTCGTATTTGAGGAAGGCCTTGAAAATGTGATTGCGAGACATAAACGTTTAGGCCAAGCAACAAGGCTTGCTGTGGAGGCATGGGGTTTGAAGAACTGCACACAAAAGGAGGAATGGCACAGTGACACTGTGACTGCTGTTGTTGTTCCTCCATACATTGACAGTGCAGAAATTGTTAGAAGGGCTTGGAAGAGATACAATTTGAGTTTAGGTCTTGGCCTCAACAAAGTTGCTGGTAAAGTCTTCAGAATTGGCCACCTTGGCAACCTAAATGAGTTGCAACTGTTGGGTTGTCTTGCTGGTGTGGAGATGATTCTGAAGGATGTTGGTTATCCAGTGAAGCTTGGAAGTGGTGTTGCAGCAGCTTCTTCATATTTGCAGAACAACATCCCTCTCATTCCTTCTCGGATTTGA

Protein sequences

Name	Description	Sequence
aminotransferase 2	aminotransferase 2 [Cucumis melo].	MDYVYGPGRNHLFVPGPVNIPEQVLRAMNRNNEDYRSPAVPALTKTLLEDVKKIFKTTSGTPFLFPTTGTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQQRLNFKVDVIESEWGEGAKLDVLAAKLAADTDHTIKAVCIVHNETATGVTNDLSLVRRILHEYRHPALFLVDGVSSICALDFRMDDWGVDVALTGSQKALSLPTGIGIVCASPRALEASKTAKSLRVFFDWKDYLKFYNLGTYWPYTPSIQLLYGLRPALDLVFEEGLENVIARHKRLGQATRLAVEAWGLKNCTQKEEWHSDTVTAVVVPPYIDSAEIVRRAWKRYNLSLGLGLNKVAGKVFRIGHLGNLNELQLLGCLAGVEMILKDVGYPVKLGSGVAAASSYLQNNIPLIPSRI

Domains

Domain	Start-End	Description	Sequence
HMMPanther: PTHR21152	1-401	PTHR21152,AMINOTRANSFERASE CLASS V	MDYVYGPGRNHLFVPGPVNIPEQVLRAMNRNNEDYRSPAVPALTKTLLEDVKKIFKTTSGTPFLFPTTGTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQQRLNFKVDVIESEWGEGAKLDVLAAKLAADTDHTIKAVCIVHNETATGVTNDLSLVRRILHEYRHPALFLVDGVSSICALDFRMDDWGVDVALTGSQKALSLPTGIGIVCASPRALEASKTAKSLRVFFDWKDYLKFYNLGTYWPYTPSIQLLYGLRPALDLVFEEGLENVIARHKRLGQATRLAVEAWGLKNCTQKEEWHSDTVTAVVVPPYIDSAEIVRRAWKRYNLSLGLGLNKVAGKVFRIGHLGNLNELQLLGCLAGVEMILKDVGYPVKLGSGVAAASSYLQNNIPLIPSRI
HMMPanther: PTHR21152:SF7	1-401	PTHR21152:SF7,SUBFAMILY NOT NAMED	MDYVYGPGRNHLFVPGPVNIPEQVLRAMNRNNEDYRSPAVPALTKTLLEDVKKIFKTTSGTPFLFPTTGTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQQRLNFKVDVIESEWGEGAKLDVLAAKLAADTDHTIKAVCIVHNETATGVTNDLSLVRRILHEYRHPALFLVDGVSSICALDFRMDDWGVDVALTGSQKALSLPTGIGIVCASPRALEASKTAKSLRVFFDWKDYLKFYNLGTYWPYTPSIQLLYGLRPALDLVFEEGLENVIARHKRLGQATRLAVEAWGLKNCTQKEEWHSDTVTAVVVPPYIDSAEIVRRAWKRYNLSLGLGLNKVAGKVFRIGHLGNLNELQLLGCLAGVEMILKDVGYPVKLGSGVAAASSYLQNNIPLIPSRI
HMMPIR: PIRSF000524 IPR024169	7-396	SPT Serine-pyruvate aminotransferase/2-aminoethylphosp	PGRNHLFVPGPVNIPEQVLRAMNRNNEDYRSPAVPALTKTLLEDVKKIFKTTSGTPFLFPTTGTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQQRLNFKVDVIESEWGEGAKLDVLAAKLAADTDHTIKAVCIVHNETATGVTNDLSLVRRILHEYRHPALFLVDGVSSICALDFRMDDWGVDVALTGSQKALSLPTGIGIVCASPRALEASKTAKSLRVFFDWKDYLKFYNLGTYWPYTPSIQLLYGLRPALDLVFEEGLENVIARHKRLGQATRLAVEAWGLKNCTQKEEWHSDTVTAVVVPPYIDSAEIVRRAWKRYNLSLGLGLNKVAGKVFRIGHLGNLNELQLLGCLAGVEMILKDVGYPVKLGSGVAAASSYLQNNIPL
superfamily: SSF53383 IPR015424	7-377	PyrdxlP-dep_Trfase_major Pyridoxal phosphate-dependent transferase, major d	PGRNHLFVPGPVNIPEQVLRAMNRNNEDYRSPAVPALTKTLLEDVKKIFKTTSGTPFLFPTTGTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQQRLNFKVDVIESEWGEGAKLDVLAAKLAADTDHTIKAVCIVHNETATGVTNDLSLVRRILHEYRHPALFLVDGVSSICALDFRMDDWGVDVALTGSQKALSLPTGIGIVCASPRALEASKTAKSLRVFFDWKDYLKFYNLGTYWPYTPSIQLLYGLRPALDLVFEEGLENVIARHKRLGQATRLAVEAWGLKNCTQKEEWHSDTVTAVVVPPYIDSAEIVRRAWKRYNLSLGLGLNKVAGKVFRIGHLGNLNELQLLGCLAGVEMILKDVGYPV
HMMPfam: PF00266 IPR000192	12-328	Aminotran_5 Aminotransferase, class V/Cysteine desulfurase	LFVPGPVNIPEQVLRAMNRNNEDYRSPAVPALTKTLLEDVKKIFKTTSGTPFLFPTTGTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQQRLNFKVDVIESEWGEGAKLDVLAAKLAADTDHTIKAVCIVHNETATGVTNDLSLVRRILHEYRHPALFLVDGVSSICALDFRMDDWGVDVALTGSQKALSLPTGIGIVCASPRALEASKTAKSLRVFFDWKDYLKFYNLGTYWPYTPSIQLLYGLRPALDLVFEEGLENVIARHKRLGQATRLAVEAWGLKNCTQKEEWHSDTVTAVVVPPYIDSAEIVRRAWK
Gene3D: G3DSA:3.40.640.10 IPR015421	21-257	PyrdxlP-dep_Trfase_major_sub1 Pyridoxal phosphate-dependent transferase, major r	PEQVLRAMNRNNEDYRSPAVPALTKTLLEDVKKIFKTTSGTPFLFPTTGTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQQRLNFKVDVIESEWGEGAKLDVLAAKLAADTDHTIKAVCIVHNETATGVTNDLSLVRRILHEYRHPALFLVDGVSSICALDFRMDDWGVDVALTGSQKALSLPTGIGIVCASPRALEASKTAKSLRVFFDWKDYLKFYNLGTYWPYTPSIQLLY
PatternScan: PS00595 IPR020578	192-212	AA_TRANSFER_CLASS_5 Aminotransferase class-V pyridoxal-phosphate bindi	VDVALTGSQKALSLPTGIGIV
Gene3D: G3DSA:3.90.1150.10 IPR015422	258-383	PyrdxlP-dep_Trfase_major_sub2 Pyridoxal phosphate-dependent transferase, major r	GLRPALDLVFEEGLENVIARHKRLGQATRLAVEAWGLKNCTQKEEWHSDTVTAVVVPPYIDSAEIVRRAWKRYNLSLGLGLNKVAGKVFRIGHLGNLNELQLLGCLAGVEMILKDVGYPVKLGSGV

Diseases

Disease	Pathogen	Avirulence gene
Downy mildew mellon

List of References

Dvir Taler, Marjana Galperin, Ido Benjamin, Yigal Cohen, David Kenigsbuch
Plant eR genes that encode photorespiratory enzymes confer resistance against disease.
Plant Cell: 2004, 16(1);172-84
PubMed:14688292 WorldCat.org DOI (P p)

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Analyses

Blast

Blast matches against Reference R-Genes. Show