PRGDB00000483 (Hm1)

Hm1
Gene Type	Reference_R-Genes,_manually_curated
GenBank	162463227 (NM_001112450)
Gene Class	Other
Domain Type
Gene Species	Zea mays
	Comment?

Zea mays Helminthosporium carbonum susceptibility1 (hm1), mRNA.

DNA Sequence

ATGGCCGAAAAGGAGAGCAACGGAGTGCGGGTGTGCGTCACCGGAGGAGCCGGGTTCATCGGCTCCTGGCTCGTCAGGAAGCTCCTCGAGAAAGGCTACACCGTCCACGCCACCCTGCGGAACACCGGGGACGAGGCGAAGGCGGGGCTGCTGCGTCGGCTGGTCCCCGGCGCAGCGGAGCGGCTGCGGTTGTTCCAGGCCGACCTCTTCGACGCCGCCACCTTCGCGCCGGCGATCGCTGGGTGCCAGTTCGTCTTCCTCGTCGCCACGCCATTCGGGCTCGATAGCGCCGGCTCCCAGTATAAGAGCACGGCGGAAGCTGTGGTGGACGCGGTGCACGCGATCCTCCGGCAATGCGAGGAGTCCAGGACGGTGAAGCGAGTGATCCACACGGCCTCCGTAGCGGCCGCCTCGCCGCTGCTGGAGGAGGAGGTCCCCGCCTCCGGCGTCGGGTACAGAGACTTCATCGACGAATCTTGTTGGACTTCGCTCAACGTTGACTATCCTCTACGAAGCGCACACTTCGACAAGTACATACTGTCGAAGCTGCAGTCGGAGCAAGAGCTCCTGAGCTACAACAACGGCGAGAGTCCGGCGTTCGAGGTGGTGACCCTGCCGCTGGGGCTCGTGGCGGGCGACACGGTCCTCGGCCGCGCCCCGGAGACGGTGGAGAGCGCCGTGGCGCCCGTGTCCCGCAGCGAGCCCTACTTCGGCCTCCTGCGCATACTGCAGCAGCTCCTGGGGTCGCTGCCGCTGGTGCACGTGGACGACGTCTGCGACGCGCTCGTCTTCTGCATGGAGCGGCGCCCCTCCGTCGCCGGCCGCTTCCTCTGCGCCGCCGCGTACCCGACGATCCACGACGTGGTCGCCCACTACGCCAGCAAGTTCCCTCACCTCGACATCTTGAAAGAGACGACGGAGGCGGTGGCGACGGTGCGGCCTGCCCGGGACAGGTTGGGCGAGCTGGGCTTCAAGTACAAGTACGGCATGGAAGAGATTCTGGATAGCAGCGTTGCCTGTGCGGCGAGATTGGGTTCCCTTGACGGATCCAAGCTCGGCCTACAGAAAGGATAA

Protein sequences

Name	Description	Sequence
Helminthosporium carbonum susceptibility1	Helminthosporium carbonum susceptibility1 [Zea mays].	MAEKESNGVRVCVTGGAGFIGSWLVRKLLEKGYTVHATLRNTGDEAKAGLLRRLVPGAAERLRLFQADLFDAATFAPAIAGCQFVFLVATPFGLDSAGSQYKSTAEAVVDAVHAILRQCEESRTVKRVIHTASVAAASPLLEEEVPASGVGYRDFIDESCWTSLNVDYPLRSAHFDKYILSKLQSEQELLSYNNGESPAFEVVTLPLGLVAGDTVLGRAPETVESAVAPVSRSEPYFGLLRILQQLLGSLPLVHVDDVCDALVFCMERRPSVAGRFLCAAAYPTIHDVVAHYASKFPHLDILKETTEAVATVRPARDRLGELGFKYKYGMEEILDSSVACAARLGSLDGSKLGLQKG

Domains

Domain	Start-End	Description	Sequence
HMMPanther: PTHR10366:SF78	1-348	PTHR10366:SF78,OS06G0651100 PROTEIN	MAEKESNGVRVCVTGGAGFIGSWLVRKLLEKGYTVHATLRNTGDEAKAGLLRRLVPGAAERLRLFQADLFDAATFAPAIAGCQFVFLVATPFGLDSAGSQYKSTAEAVVDAVHAILRQCEESRTVKRVIHTASVAAASPLLEEEVPASGVGYRDFIDESCWTSLNVDYPLRSAHFDKYILSKLQSEQELLSYNNGESPAFEVVTLPLGLVAGDTVLGRAPETVESAVAPVSRSEPYFGLLRILQQLLGSLPLVHVDDVCDALVFCMERRPSVAGRFLCAAAYPTIHDVVAHYASKFPHLDILKETTEAVATVRPARDRLGELGFKYKYGMEEILDSSVACAARLGSLD
HMMPanther: PTHR10366	1-348	PTHR10366,NAD DEPENDENT EPIMERASE/DEHYDRATASE	MAEKESNGVRVCVTGGAGFIGSWLVRKLLEKGYTVHATLRNTGDEAKAGLLRRLVPGAAERLRLFQADLFDAATFAPAIAGCQFVFLVATPFGLDSAGSQYKSTAEAVVDAVHAILRQCEESRTVKRVIHTASVAAASPLLEEEVPASGVGYRDFIDESCWTSLNVDYPLRSAHFDKYILSKLQSEQELLSYNNGESPAFEVVTLPLGLVAGDTVLGRAPETVESAVAPVSRSEPYFGLLRILQQLLGSLPLVHVDDVCDALVFCMERRPSVAGRFLCAAAYPTIHDVVAHYASKFPHLDILKETTEAVATVRPARDRLGELGFKYKYGMEEILDSSVACAARLGSLD
superfamily: SSF51735	7-343	NAD(P)-bd	NGVRVCVTGGAGFIGSWLVRKLLEKGYTVHATLRNTGDEAKAGLLRRLVPGAAERLRLFQADLFDAATFAPAIAGCQFVFLVATPFGLDSAGSQYKSTAEAVVDAVHAILRQCEESRTVKRVIHTASVAAASPLLEEEVPASGVGYRDFIDESCWTSLNVDYPLRSAHFDKYILSKLQSEQELLSYNNGESPAFEVVTLPLGLVAGDTVLGRAPETVESAVAPVSRSEPYFGLLRILQQLLGSLPLVHVDDVCDALVFCMERRPSVAGRFLCAAAYPTIHDVVAHYASKFPHLDILKETTEAVATVRPARDRLGELGFKYKYGMEEILDSSVACAAR
Gene3D: G3DSA:3.40.50.720 IPR016040	9-294	NAD(P)-bd NAD(P)-binding domain	VRVCVTGGAGFIGSWLVRKLLEKGYTVHATLRNTGDEAKAGLLRRLVPGAAERLRLFQADLFDAATFAPAIAGCQFVFLVATPFGLDSAGSQYKSTAEAVVDAVHAILRQCEESRTVKRVIHTASVAAASPLLEEEVPASGVGYRDFIDESCWTSLNVDYPLRSAHFDKYILSKLQSEQELLSYNNGESPAFEVVTLPLGLVAGDTVLGRAPETVESAVAPVSRSEPYFGLLRILQQLLGSLPLVHVDDVCDALVFCMERRPSVAGRFLCAAAYPTIHDVVAHYAS
HMMPfam: PF01370 IPR001509	11-269	Epimerase NAD-dependent epimerase/dehydratase	VCVTGGAGFIGSWLVRKLLEKGYTVHATLRNTGDEAKAGLLRRLVPGAAERLRLFQADLFDAATFAPAIAGCQFVFLVATPFGLDSAGSQYKSTAEAVVDAVHAILRQCEESRTVKRVIHTASVAAASPLLEEEVPASGVGYRDFIDESCWTSLNVDYPLRSAHFDKYILSKLQSEQELLSYNNGESPAFEVVTLPLGLVAGDTVLGRAPETVESAVAPVSRSEPYFGLLRILQQLLGSLPLVHVDDVCDALVFCMERR

Diseases

Disease	Pathogen	Avirulence gene
Leaf Spot

List of References

Liqing Zhang, Andrew S Peek, Detiger Dunams, Brandon S Gaut
Population genetics of duplicated disease-defense genes, hm1 and hm2, in maize (Zea mays ssp. mays L.) and its wild ancestor (Zea mays ssp. parviglumis).
Genetics: 2002, 162(2);851-60
PubMed:12399395 WorldCat.org (P p)

D S Multani, R B Meeley, A H Paterson, J Gray, S P Briggs, G S Johal
Plant-pathogen microevolution: molecular basis for the origin of a fungal disease in maize.
Proc. Natl. Acad. Sci. U.S.A.: 1998, 95(4);1686-91
PubMed:9465077 WorldCat.org (P p)

G S Johal, S P Briggs
Reductase activity encoded by the HM1 disease resistance gene in maize.
Science: 1992, 258(5084);985-7
PubMed:1359642 WorldCat.org (P p)

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Analyses

Blast

Blast matches against Reference R-Genes. Show