PRGDB00061432 (MLA1)
| MLA1 | |
|---|---|
| Gene Type | Reference_R-Genes,_manually_curated |
| GenBank | 270267804 (GU245961) |
| Gene Class | CNL |
| Domain Type | NBS, LRR, Others |
| Gene Species | Hordeum vulgare |
DNA Sequence
ATGGAGGTCGTCACGGGTGCCATGGGCAGCCTGCTCCCCAAGCTGGGCCAACTGCTCCTCGATGAGTACAACTTGCACAAGCGCGTCAAGAAAGATGTCGAGTTCCTCACGAAGGAGCTTGAGAGCATGCACGCTGCCCTCATCAAGGTTGGCAAGGTGCCACGGGACCATCTCGACAGGCAAGTAAAGCTCTGGGCCGACGAGGTCAGAGAGCTCTCCTACAACATGGAGGATGTCGTTGACAAGTTCCTCGTGCGCGTCGACGGCAACTCCGGCAGATTCAAGGAGCTCAAGAACAAGATGATCGGCTTGTTCAAGAAAGGCAAGAATCACCATCGGATAGCTGACGCGATCAAGGAAATCAAGGAGCAACTCCAGGAGGTGGCTGCTAGGCGTGACAGGAACGAGGTACTTGTTCCTAATCCTATGGAACCAATTGCTATCGATCCTTGTCTTCGAGCTTTGTACGCAGAAGCGTCGGAGCTAGTTGGCATATATGGCAAGAGGGATCAGGAGCTCATGAGGTTGCTCTCCATGGAGGGTGATGATGCCTCTGAGAAGAGACTGAAGAAGGTCTCCATTGTTGGATTTGGAGGGTTGGGCAAGACCACTCTTGCAAGAGCAGTATACGACAAGATTAAAGGTGATTTCGATTGTGGGGCATTTGTTCCGGTCGGTCAGAACCCTGACATGAAGAAGGTTTTAAGGGATATCCTCATTGATCTCGGTAACCCTCTCTCGGACCTTGCGATGCTGGATGCCAATCAGCTTATTAAAAAGCTTCGTGATTTTCTAGAGAACAAAAGGTATCTTGTCATAATTGATGATATATGGGATGACAAATTGTGGGAAGCCATCAACTTTGCTTTCTCCAAGAGGAATAATCTAGGCAGTCGGCTAATCATCACAACCCGCATTGTTAGTGTCTCCAATTCATGTTGTTCGTCAGCTCATGATTCAGTTTATCAAATGAAACCTCTTTCTACTGATGACTCCAGAAGGCTCTTCCATAAAAGAATATTTCCGGACGATAGTGGATGTCCAAATGAATTTGAACAAGTGTCAGAAGATTTATTGAAAAAATGTGGTGGGGTACCGCTAGCCATCATTACTATTGCTAGTGCTTTGGCTGGTGGCCAGCAGATGAAACCAAAGTGTGAGTGGGATATTTTACTCCAGTCCCTTGGCTCTGGACTAACAGAAGATAACAGTTTAGAGGAGATGCGGAGGATACTATCTTTCAGCTATTATGATCTACCTTATCATCTGAGAACTTGTCTATTGTACCTATGTATATACCCAGAAGACAGCCAGATTGATAGAGATAGACTGATATGGAAGTGGGTGGCTGAAGGATTTGTCCACTGTGGAAACCAAGGGACTAGCCTATTTTTGCTCGGATTAAACTACTTCAACCAGCTCATTAACAGAAGTATGATCCAGCCAATATATGGTTATGCAGGTGAGGTATATGCTTGTTGTGTACATGATATGGTTCTTGATCTTATCTGCAACTTGTCACATGAAGCAAAGTTTGTTAATGTATTGGATGGCACTGGGGATAGCATGTCCTTACAAGGCAATGTTCGTCGTTTGTCCCTTCAACATAGAAACAAAGATCATCAAGGCACACCTCTCAGAAATTTCAGGGGTATATCACGAGTGAGGTCCATTACTAATTTTGGATCTGCTATTAATATCATGCCAGTCCTGTCAAGGTTTGAAGTTCTGCGTGTACTTGATTTGACGGACTGTAATCTGGGAGAAAGTAGCAGCCTGCAACTTAACCTCAAGGGTTTTGGACACTTAATTCACCTGAGGTACCTTGGTCTAGCAGGTACTGGAATCATGAAACTATCAGCTGAGATAGGAAATCTGCAGTTTTTGGAGGTCTTGGATCTAGGAGGCAACAATGGGCTAGAAGAATTGCCACCCATTGTTTATAATTTGAGAAGATTAATCTACCTAAATGTTCCCTTTATGGTGGTTCCAGCTGGTGTGTTGCAGAATCTGACATCCATAGAAGTGTTGAGGGGAATATTGGTCTCTTTGAACACTGTCGCACAAGAGCTTGGCAACATAGCAATGCTGAGGGAGCTTGAGATTTGCTTCAAGGAGGGTAGTTTGGCTTTGTATGAATGTTTTGTGAAGTCTCTTTGCAGCCTACATCAGATCGAAAGTCTATGTATTGATTGCAATCCCAGAGAAACATCATCTTTTGAACTGATGGATCTCTTGGGAGAACGCTGGGTGCCTCCTGTACATATCCGCAAATTTGACTCAAGCTTTCCCAGCCAACTCTCTGCACTGCGAGGGTGGATAAAGAAAGACCCCTCGCATCTCTCGAACCTCTCCGATTTATTCCTCAGACCAGTGAAGGAAGTGCAGCAGGAGGACGTGGAAATCATTGGGGGGCTGTTGTCCCTTCGCCGTCTCTGGATAAAGAGCACCCACCAAACACAACGGCTGCTAGATGGGTTCCGCTGTCTGTTACGCTTTTCCTTGGATTGTGGATCAGCAGCGCAGATAATGTTTGAACCAGGAGCATTGCCGAGGGTGGAAATAGTTATATTCAGTCTGGGCGTGCGGGTGGCGAAAGAGGATGGTAACTGTCGCTTCGACTTGGGCCTGCAGGGGAACCTGCTCTCCCTTCGGCAACGTGTCTGGGTTAAAATCTATTGTGGTGGAGCGACGGTGGGTGAGGCAAAGGAAGCGGAGGCTGCGGTGCGGCTCGCGCTCGACTCCCATCCCAACCATCCCCCGATTTATATTGAGATGAGGCCGCGTATACAAGAAGATGCGCACGATGACGATTTGTGTAAGGACATGACGGAGAACTGA
Protein sequences
| Name | Description | Sequence |
|---|---|---|
| MLA1 | MLA1 [Hordeum vulgare]. | MEVVTGAMGSLLPKLGQLLLDEYNLHKRVKKDVEFLTKELESMHAALIKVGKVPRDHLDRQVKLWADEVRELSYNMEDVVDKFLVRVDGNSGRFKELKNKMIGLFKKGKNHHRIADAIKEIKEQLQEVAARRDRNEVLVPNPMEPIAIDPCLRALYAEASELVGIYGKRDQELMRLLSMEGDDASEKRLKKVSIVGFGGLGKTTLARAVYDKIKGDFDCGAFVPVGQNPDMKKVLRDILIDLGNPLSDLAMLDANQLIKKLRDFLENKRYLVIIDDIWDDKLWEAINFAFSKRNNLGSRLIITTRIVSVSNSCCSSAHDSVYQMKPLSTDDSRRLFHKRIFPDDSGCPNEFEQVSEDLLKKCGGVPLAIITIASALAGGQQMKPKCEWDILLQSLGSGLTEDNSLEEMRRILSFSYYDLPYHLRTCLLYLCIYPEDSQIDRDRLIWKWVAEGFVHCGNQGTSLFLLGLNYFNQLINRSMIQPIYGYAGEVYACCVHDMVLDLICNLSHEAKFVNVLDGTGDSMSLQGNVRRLSLQHRNKDHQGTPLRNFRGISRVRSITNFGSAINIMPVLSRFEVLRVLDLTDCNLGESSSLQLNLKGFGHLIHLRYLGLAGTGIMKLSAEIGNLQFLEVLDLGGNNGLEELPPIVYNLRRLIYLNVPFMVVPAGVLQNLTSIEVLRGILVSLNTVAQELGNIAMLRELEICFKEGSLALYECFVKSLCSLHQIESLCIDCNPRETSSFELMDLLGERWVPPVHIRKFDSSFPSQLSALRGWIKKDPSHLSNLSDLFLRPVKEVQQEDVEIIGGLLSLRRLWIKSTHQTQRLLDGFRCLLRFSLDCGSAAQIMFEPGALPRVEIVIFSLGVRVAKEDGNCRFDLGLQGNLLSLRQRVWVKIYCGGATVGEAKEAEAAVRLALDSHPNHPPIYIEMRPRIQEDAHDDDLCKDMTEN |
Domains
| Domain | Start-End | Description | Sequence
|
|---|---|---|---|
| HMMPanther: PTHR23155:SF217 | 4-937 | PTHR23155:SF217,OS11G0657900 PROTEIN | VTGAMGSLLPKLGQLLLDEYNLHKRVKKDVEFLTKELESMHAALIKVGKVPRDHLDRQVKLWADEVRELSYNMEDVVDKFLVRVDGNSGRFKELKNKMIGLFKKGKNHHRIADAIKEIKEQLQEVAARRDRNEVLVPNPMEPIAIDPCLRALYAEASELVGIYGKRDQELMRLLSMEGDDASEKRLKKVSIVGFGGLGKTTLARAVYDKIKGDFDCGAFVPVGQNPDMKKVLRDILIDLGNPLSDLAMLDANQLIKKLRDFLENKRYLVIIDDIWDDKLWEAINFAFSKRNNLGSRLIITTRIVSVSNSCCSSAHDSVYQMKPLSTDDSRRLFHKRIFPDDSGCPNEFEQVSEDLLKKCGGVPLAIITIASALAGGQQMKPKCEWDILLQSLGSGLTEDNSLEEMRRILSFSYYDLPYHLRTCLLYLCIYPEDSQIDRDRLIWKWVAEGFVHCGNQGTSLFLLGLNYFNQLINRSMIQPIYGYAGEVYACCVHDMVLDLICNLSHEAKFVNVLDGTGDSMSLQGNVRRLSLQHRNKDHQGTPLRNFRGISRVRSITNFGSAINIMPVLSRFEVLRVLDLTDCNLGESSSLQLNLKGFGHLIHLRYLGLAGTGIMKLSAEIGNLQFLEVLDLGGNNGLEELPPIVYNLRRLIYLNVPFMVVPAGVLQNLTSIEVLRGILVSLNTVAQELGNIAMLRELEICFKEGSLALYECFVKSLCSLHQIESLCIDCNPRETSSFELMDLLGERWVPPVHIRKFDSSFPSQLSALRGWIKKDPSHLSNLSDLFLRPVKEVQQEDVEIIGGLLSLRRLWIKSTHQTQRLLDGFRCLLRFSLDCGSAAQIMFEPGALPRVEIVIFSLGVRVAKEDGNCRFDLGLQGNLLSLRQRVWVKIYCGGATVGEAKEAEAAVRLALDSHPNHPPIYIEMRPRIQEDAHDD |
| HMMPanther: PTHR23155 | 4-937 | PTHR23155,LRR,LEUCINE-RICH REPEAT-CONTAINING PROTEIN | VTGAMGSLLPKLGQLLLDEYNLHKRVKKDVEFLTKELESMHAALIKVGKVPRDHLDRQVKLWADEVRELSYNMEDVVDKFLVRVDGNSGRFKELKNKMIGLFKKGKNHHRIADAIKEIKEQLQEVAARRDRNEVLVPNPMEPIAIDPCLRALYAEASELVGIYGKRDQELMRLLSMEGDDASEKRLKKVSIVGFGGLGKTTLARAVYDKIKGDFDCGAFVPVGQNPDMKKVLRDILIDLGNPLSDLAMLDANQLIKKLRDFLENKRYLVIIDDIWDDKLWEAINFAFSKRNNLGSRLIITTRIVSVSNSCCSSAHDSVYQMKPLSTDDSRRLFHKRIFPDDSGCPNEFEQVSEDLLKKCGGVPLAIITIASALAGGQQMKPKCEWDILLQSLGSGLTEDNSLEEMRRILSFSYYDLPYHLRTCLLYLCIYPEDSQIDRDRLIWKWVAEGFVHCGNQGTSLFLLGLNYFNQLINRSMIQPIYGYAGEVYACCVHDMVLDLICNLSHEAKFVNVLDGTGDSMSLQGNVRRLSLQHRNKDHQGTPLRNFRGISRVRSITNFGSAINIMPVLSRFEVLRVLDLTDCNLGESSSLQLNLKGFGHLIHLRYLGLAGTGIMKLSAEIGNLQFLEVLDLGGNNGLEELPPIVYNLRRLIYLNVPFMVVPAGVLQNLTSIEVLRGILVSLNTVAQELGNIAMLRELEICFKEGSLALYECFVKSLCSLHQIESLCIDCNPRETSSFELMDLLGERWVPPVHIRKFDSSFPSQLSALRGWIKKDPSHLSNLSDLFLRPVKEVQQEDVEIIGGLLSLRRLWIKSTHQTQRLLDGFRCLLRFSLDCGSAAQIMFEPGALPRVEIVIFSLGVRVAKEDGNCRFDLGLQGNLLSLRQRVWVKIYCGGATVGEAKEAEAAVRLALDSHPNHPPIYIEMRPRIQEDAHDD |
| superfamily: SSF52540 | 145-402 | SSF52540 | PIAIDPCLRALYAEASELVGIYGKRDQELMRLLSMEGDDASEKRLKKVSIVGFGGLGKTTLARAVYDKIKGDFDCGAFVPVGQNPDMKKVLRDILIDLGNPLSDLAMLDANQLIKKLRDFLENKRYLVIIDDIWDDKLWEAINFAFSKRNNLGSRLIITTRIVSVSNSCCSSAHDSVYQMKPLSTDDSRRLFHKRIFPDDSGCPNEFEQVSEDLLKKCGGVPLAIITIASALAGGQQMKPKCEWDILLQSLGSGLTED |
| Gene3D: G3DSA:3.40.50.300 | 174-304 | G3DSA:3.40.50.300 | MRLLSMEGDDASEKRLKKVSIVGFGGLGKTTLARAVYDKIKGDFDCGAFVPVGQNPDMKKVLRDILIDLGNPLSDLAMLDANQLIKKLRDFLENKRYLVIIDDIWDDKLWEAINFAFSKRNNLGSRLIITT |
| HMMPfam: PF00931 IPR002182
|
186-457 | NB-ARC,NBS NB-ARC
|
EKRLKKVSIVGFGGLGKTTLARAVYDKIKGDFDCGAFVPVGQNPDMKKVLRDILIDLGNPLSDLAMLDANQLIKKLRDFLENKRYLVIIDDIWDDKLWEAINFAFSKRNNLGSRLIITTRIVSVSNSCCSSAHDSVYQMKPLSTDDSRRLFHKRIFPDDSGCPNEFEQVSEDLLKKCGGVPLAIITIASALAGGQQMKPKCEWDILLQSLGSGLTEDNSLEEMRRILSFSYYDLPYHLRTCLLYLCIYPEDSQIDRDRLIWKWVAEGFVHCG |
| FPrintScan: PR00364 IPR000767
|
191-206 | DISEASERSIST Disease resistance protein
|
KVSIVGFGGLGKTTLA |
| FPrintScan: PR00364 IPR000767
|
264-278 | DISEASERSIST Disease resistance protein
|
FLENKRYLVIIDDIW |
| FPrintScan: PR00364 IPR000767
|
362-376 | DISEASERSIST Disease resistance protein
|
CGGVPLAIITIASAL |
| superfamily: SSF52047 | 527-820 | SSF52047,LRR | GNVRRLSLQHRNKDHQGTPLRNFRGISRVRSITNFGSAINIMPVLSRFEVLRVLDLTDCNLGESSSLQLNLKGFGHLIHLRYLGLAGTGIMKLSAEIGNLQFLEVLDLGGNNGLEELPPIVYNLRRLIYLNVPFMVVPAGVLQNLTSIEVLRGILVSLNTVAQELGNIAMLRELEICFKEGSLALYECFVKSLCSLHQIESLCIDCNPRETSSFELMDLLGERWVPPVHIRKFDSSFPSQLSALRGWIKKDPSHLSNLSDLFLRPVKEVQQEDVEIIGGLLSLRRLWIKSTHQT |
| Gene3D: G3DSA:3.80.10.10 | 553-719 | G3DSA:3.80.10.10 | SRVRSITNFGSAINIMPVLSRFEVLRVLDLTDCNLGESSSLQLNLKGFGHLIHLRYLGLAGTGIMKLSAEIGNLQFLEVLDLGGNNGLEELPPIVYNLRRLIYLNVPFMVVPAGVLQNLTSIEVLRGILVSLNTVAQELGNIAMLRELEICFKEGSLALYECFVKSL |
| FPrintScan: PR00364 IPR000767
|
624-640 | DISEASERSIST Disease resistance protein
|
GNLQFLEVLDLGGNNGL |
| HMMPfam: PF00560 IPR001611
|
629-645 | LRR_1 Leucine-rich repeat
|
LEVLDLGGNNGLEELPP |
| Gene3D: G3DSA:3.80.10.10 | 779-818 | G3DSA:3.80.10.10 | SHLSNLSDLFLRPVKEVQQEDVEIIGGLLSLRRLWIKSTH |
Diseases
| Disease | Pathogen | Avirulence gene |
|---|---|---|
| Powdery mildew (barley) | Blumeria graminis |
List of Contributions
There has not been any contribution yet.
