PRGDB00061467 (RAC1)
| RAC1 | |
|---|---|
| Gene Type | Reference_R-Genes,_manually_curated |
| GenBank | 41387773 (AY522496) |
| Gene Class | TNL |
| Domain Type | NBS, TIR, LRR, Others |
| Chromosome | 1 |
| Gene Species | Arabidopsis thaliana |
DNA Sequence
ATGGCTTCGTCATCTTCTTCTCACAATTGGTTATATGATGTTTTCTTGAGCTTCAGAGGGGAAGACGTCCGCGTAACATTCCGTAGCCACTTTCTCAAAGAGCTTGATCGGAAACTAATCACTGCTTTCAGAGACAATGAGATCGAGAGAAGCCACTCTCTCTGGCCCGATCTTGAACAAGCCATCAAGGAATCCAGGATCGCTGTGGTCGTTTTCTCCATAAACTACGCTTCATCGAGCTGGTGTCTTAACGAGTTGCTGGAGATTGTAAACTGCAATGATAAAATTGTCATACCAGTTTTCTACCATGTGGATCCTTCCCAAGTGAGGCATCAAATCGGCGACTTCGGAAAGATCTTTGAAAATACTTGCAAGAGACAAACAGATGAGGAAGTGAAAAATCAATGGAAGAAAGCGTTGACTCTTGTAGCTAATATGCTTGGATTTGACTCTGCCAAATGGAACGACGAAGCAAAAATGATTGAAGAAATAGCCAATGATGTTTTGGGTAAACTGCTTTTAACTACACCTAAGGATTCTGAGGAACTTGTTGGCATCGAAGATCACATCGCTGAAATGAGTTTACTGCTGCAACTGGAATCTGAAGAAGTGAGAATGGTTGGTATATCGGGTTCATCAGGGATTGGTAAGACTACCATTGCAAGAGCTCTGTTTAAACGACTTTCTCGACATTTCCAAGGTAGCACTTTCATCGACAGGGCTTTTGTATCTAATAGTCGGAATATTTATAGTGGCGCCAATCCGGACGACCCCAATATGAAGTTGCAGCTACAAGGACACTTCCTATCTGAAATTCTCGGGAAAAAAGACATAAAGATAGATGATCCAGCTGCACTGGAAGAGAGGCTAAAGCACCAAAAAGTTCTTATCATTATTGATGATTTGGATGATATAATGGTACTAGATACATTAGTGGGTCAAACTCAATGGTTTGGATATGGGAGCAGAATCATTGTGGTTACAAATGATAAGCACTTCTTGACTGCTCATGGGATTGATCATATTTATGAAGTCAGTTTCCCAACTGATGTGCATGCTTATCAGATGTTATGTCAATCTGCATTCAAGCAAAACTATGCTCCTAAAGGTTTTGAGGATCTTGTAGTTGATGTAGTAAGACATGCGGGCAGTTTTCCTTTGGGTCTTAATCTTTTGGGTAAATATTTGCGGAGGAGGGATATGGAATATTGGATGGATATGCTGCCAAGGCTTGAGAATGGTCTACGTATAGACGGTAAAATTGAAAAAATACTAAGAATCAGCTATGATGGGTTAGAGAGTGAAGATCAAGAGATATTTCGTCATATCGCATGTCTTTTCAATCATATGGAAGTCACAACCATCAAGTCCTTGCTGGCAGATAGTGATGTTAGTTTTGCACTAGAAAACCTAGCTGATAAGTCCCTCATTCATGTCAGACAAGGTTATGTGGTGATGCACCGTTCGCTACAAGAAATGGGTAGAAAAATTGTTCGCATTCAGTCCATTGACAAACCTGGAGAACGAGAATTTCTGGTGGATCCAAATGATATACATGATATACTCAATGCATGCACTGGTACTCAAAAGGTTTTAGGTATATCACTGGATACAAGGAATATTCGTGAGTTGGATGTACATCAGAGGGCCTTTAAAGGGATGTCTAATCTCCGTTTCTTAGAAATTAAGAACTTTCGTTTGAAAGAAGACAGTTTGCATTTACCTCCAAGTTTCGACTATTTGCCCCGTACACTCAAACTATTGAGCTGGTCCAAATTTCCAATGAGGTGTATGCCTTTTGATTTTCGTCCTGAAAACCTTGTCAAGCTCGAAATGAAGTACAGCAAGCTACATAAGCTATGGGAAGGAGATGTGCCACTTACATGTCTAAAGGAAATGGATCTGTACGCATCATCAAACCTGAAAGTAATTCCAGATCTTTCCAAGGCTACTAATCTCGAAATACTTAATCTTCAGTTTTGCCTCAGTTTAGTCGAGCTCCCGTCCTCTATACGAAATCTCAATAAACTGTTGAACTTGGACATGCTAGACTGCAAAAGTCTGAAAATTCTTCCTACCGGATTCAACCTCAAATCTCTTGACCGCCTCAATTTCAGTCACTGCTCAAAGTTGAAGACTTTTCCCAAATTCTCGACCAACATCTCAGTTCTCAATCTATCTCAAACAAACATTGAAGAATTCCCTTCTAATTTACATCTGAAGAATCTTGTTAAGTTTAGCATATCAAAAGAAGAGAGTGATGTGAAACAATGGGAAGGAGAGAAGCCGCTTACGCCCTTCCTGGCGATGATGTTGTCTCCCACTTTGACGAGCTTGCATCTCGAGAATCTCCCAAGTTTGGTGGAGCTTCCTTCCTCATTTCAGAATCTCAATCAACTGAAGCGCTTGTTCATTGTCCGATGCATAAATCTGGAGACTCTGCCCACCGGAATCAACCTCCAATCTCTCGATAGCCTTAGTTTCAAGGGATGCTCACGGTTGAGGAGCTTTCCTGAAATCTCAACCAACATCTCAGTGCTCTATCTAGACGAAACAGCGATTGAAGATGTTCCTTGGTGGATCGAGAAATTCTCTAACCTCACTGAGCTAAGCATGCACAGTTGCAGCAGGCTAAAATGGGTGTTCCTACACATGTCTAAACTGAAACATCTTAAGGAAGCTTTGTTTCCAAATTGTGGGAAATTGACCAGAGTTGAATTGAGTGGATATCCAAGTGGGATGGAGGTGATGAAAGCAGACAATATTGACACAGCCTCCTCTTCTCTTCCTAAAGTCGTACTCAGTTTCTTGGACTGCTTCAACTTGGATCCAGAAACTGTCCTTCATCACCAAGAATCAATTATTTTCAACTACATGTTATTTACAGGGAAAGAAGAAGTGCCATCATATTTCACTTACCGTACTACTGGAAGCTCCTCTCTGACCATTCCTCTACTTCACGTCCATCTCTCCCAACCATTCTTCAGATTTAGGATTGGCGCATTGGTAAAGAATAAGGAGATGCCAGGGATCGAGGTAAAATGTGAGTTCAAAGACAGATTTGGGAACAACTTTGATTATTACATTTATTTCGGAGTTCATAATCATAGATATTATAAAGAGGATGGCTATAATATAGCTATATTGGACTGTCGTATCCCTCTAAACGAAGATAATGCTGCTCTAGCTCAACGGAACTACTACGATCATGTGGATATAAAGATTGAGCAATTATACGAAACATATAGTGATATTGAACAATGGGGTATACGACTCTTAGAGGACTGTTCATCAGCGGAGACTCGACTTGATAATTATTCAAACAGTACTCTTCCACATGTTTCTGAAGCCGAAGAAGGCAATATAGGGTATACACCTCTTCAAGGACTTGTTAATGAGATTGAACACAGTGAAGAGCCTGGAGATATCAATGTAGAAACTGAGAGAAGCACGAAGCGCATGCGGCTATATCACTTCATATAA
Protein sequences
| Name | Description | Sequence |
|---|---|---|
| TIR-NBS-LRR | TIR-NBS-LRR [Arabidopsis thaliana]. | MASSSSSHNWLYDVFLSFRGEDVRVTFRSHFLKELDRKLITAFRDNEIERSHSLWPDLEQAIKESRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKALTLVANMLGFDSAKWNDEAKMIEEIANDVLGKLLLTTPKDSEELVGIEDHIAEMSLLLQLESEEVRMVGISGSSGIGKTTIARALFKRLSRHFQGSTFIDRAFVSNSRNIYSGANPDDPNMKLQLQGHFLSEILGKKDIKIDDPAALEERLKHQKVLIIIDDLDDIMVLDTLVGQTQWFGYGSRIIVVTNDKHFLTAHGIDHIYEVSFPTDVHAYQMLCQSAFKQNYAPKGFEDLVVDVVRHAGSFPLGLNLLGKYLRRRDMEYWMDMLPRLENGLRIDGKIEKILRISYDGLESEDQEIFRHIACLFNHMEVTTIKSLLADSDVSFALENLADKSLIHVRQGYVVMHRSLQEMGRKIVRIQSIDKPGEREFLVDPNDIHDILNACTGTQKVLGISLDTRNIRELDVHQRAFKGMSNLRFLEIKNFRLKEDSLHLPPSFDYLPRTLKLLSWSKFPMRCMPFDFRPENLVKLEMKYSKLHKLWEGDVPLTCLKEMDLYASSNLKVIPDLSKATNLEILNLQFCLSLVELPSSIRNLNKLLNLDMLDCKSLKILPTGFNLKSLDRLNFSHCSKLKTFPKFSTNISVLNLSQTNIEEFPSNLHLKNLVKFSISKEESDVKQWEGEKPLTPFLAMMLSPTLTSLHLENLPSLVELPSSFQNLNQLKRLFIVRCINLETLPTGINLQSLDSLSFKGCSRLRSFPEISTNISVLYLDETAIEDVPWWIEKFSNLTELSMHSCSRLKWVFLHMSKLKHLKEALFPNCGKLTRVELSGYPSGMEVMKADNIDTASSSLPKVVLSFLDCFNLDPETVLHHQESIIFNYMLFTGKEEVPSYFTYRTTGSSSLTIPLLHVHLSQPFFRFRIGALVKNKEMPGIEVKCEFKDRFGNNFDYYIYFGVHNHRYYKEDGYNIAILDCRIPLNEDNAALAQRNYYDHVDIKIEQLYETYSDIEQWGIRLLEDCSSAETRLDNYSNSTLPHVSEAEEGNIGYTPLQGLVNEIEHSEEPGDINVETERSTKRMRLYHFI |
Domains
| Domain | Start-End | Description | Sequence
|
|---|---|---|---|
| superfamily: SSF52200 IPR000157
|
1-149 | TIR Toll/interleukin-1 receptor homology (TIR) domain
|
MASSSSSHNWLYDVFLSFRGEDVRVTFRSHFLKELDRKLITAFRDNEIERSHSLWPDLEQAIKESRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKALTLVANMLGF |
| Gene3D: G3DSA:3.40.50.10140 | 8-140 | G3DSA:3.40.50.10140 | HNWLYDVFLSFRGEDVRVTFRSHFLKELDRKLITAFRDNEIERSHSLWPDLEQAIKESRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKAL |
| ProfileScan: PS50104 IPR000157
|
10-146 | TIR Toll/interleukin-1 receptor homology (TIR) domain
|
WLYDVFLSFRGEDVRVTFRSHFLKELDRKLITAFRDNEIERSHSLWPDLEQAIKESRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKALTLVANM |
| HMMSmart: SM00255 IPR000157
|
11-146 | TIR Toll/interleukin-1 receptor homology (TIR) domain
|
LYDVFLSFRGEDVRVTFRSHFLKELDRKLITAFRDNEIERSHSLWPDLEQAIKESRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKALTLVANM |
| HMMPfam: PF01582 IPR000157
|
14-140 | TIR Toll/interleukin-1 receptor homology (TIR) domain
|
VFLSFRGEDVRVTFRSHFLKELDRKLITAFRDNEIERSHSLWPDLEQAIKESRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKAL |
| HMMPanther: PTHR11017:SF20 | 32-1155 | PTHR11017:SF20,SUBFAMILY NOT NAMED | LKELDRKLITAFRDNEIERSHSLWPDLEQAIKESRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKALTLVANMLGFDSAKWNDEAKMIEEIANDVLGKLLLTTPKDSEELVGIEDHIAEMSLLLQLESEEVRMVGISGSSGIGKTTIARALFKRLSRHFQGSTFIDRAFVSNSRNIYSGANPDDPNMKLQLQGHFLSEILGKKDIKIDDPAALEERLKHQKVLIIIDDLDDIMVLDTLVGQTQWFGYGSRIIVVTNDKHFLTAHGIDHIYEVSFPTDVHAYQMLCQSAFKQNYAPKGFEDLVVDVVRHAGSFPLGLNLLGKYLRRRDMEYWMDMLPRLENGLRIDGKIEKILRISYDGLESEDQEIFRHIACLFNHMEVTTIKSLLADSDVSFALENLADKSLIHVRQGYVVMHRSLQEMGRKIVRIQSIDKPGEREFLVDPNDIHDILNACTGTQKVLGISLDTRNIRELDVHQRAFKGMSNLRFLEIKNFRLKEDSLHLPPSFDYLPRTLKLLSWSKFPMRCMPFDFRPENLVKLEMKYSKLHKLWEGDVPLTCLKEMDLYASSNLKVIPDLSKATNLEILNLQFCLSLVELPSSIRNLNKLLNLDMLDCKSLKILPTGFNLKSLDRLNFSHCSKLKTFPKFSTNISVLNLSQTNIEEFPSNLHLKNLVKFSISKEESDVKQWEGEKPLTPFLAMMLSPTLTSLHLENLPSLVELPSSFQNLNQLKRLFIVRCINLETLPTGINLQSLDSLSFKGCSRLRSFPEISTNISVLYLDETAIEDVPWWIEKFSNLTELSMHSCSRLKWVFLHMSKLKHLKEALFPNCGKLTRVELSGYPSGMEVMKADNIDTASSSLPKVVLSFLDCFNLDPETVLHHQESIIFNYMLFTGKEEVPSYFTYRTTGSSSLTIPLLHVHLSQPFFRFRIGALVKNKEMPGIEVKCEFKDRFGNNFDYYIYFGVHNHRYYKEDGYNIAILDCRIPLNEDNAALAQRNYYDHVDIKIEQLYETYSDIEQWGIRLLEDCSSAETRLDNYSNSTLPHVSEAEEGNIGYTPLQGLVNEIEHSEEPGDINVETERSTKRMR |
| HMMPanther: PTHR11017 | 32-1155 | PTHR11017,LEUCINE-RICH REPEAT-CONTAINING PROTEIN | LKELDRKLITAFRDNEIERSHSLWPDLEQAIKESRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKALTLVANMLGFDSAKWNDEAKMIEEIANDVLGKLLLTTPKDSEELVGIEDHIAEMSLLLQLESEEVRMVGISGSSGIGKTTIARALFKRLSRHFQGSTFIDRAFVSNSRNIYSGANPDDPNMKLQLQGHFLSEILGKKDIKIDDPAALEERLKHQKVLIIIDDLDDIMVLDTLVGQTQWFGYGSRIIVVTNDKHFLTAHGIDHIYEVSFPTDVHAYQMLCQSAFKQNYAPKGFEDLVVDVVRHAGSFPLGLNLLGKYLRRRDMEYWMDMLPRLENGLRIDGKIEKILRISYDGLESEDQEIFRHIACLFNHMEVTTIKSLLADSDVSFALENLADKSLIHVRQGYVVMHRSLQEMGRKIVRIQSIDKPGEREFLVDPNDIHDILNACTGTQKVLGISLDTRNIRELDVHQRAFKGMSNLRFLEIKNFRLKEDSLHLPPSFDYLPRTLKLLSWSKFPMRCMPFDFRPENLVKLEMKYSKLHKLWEGDVPLTCLKEMDLYASSNLKVIPDLSKATNLEILNLQFCLSLVELPSSIRNLNKLLNLDMLDCKSLKILPTGFNLKSLDRLNFSHCSKLKTFPKFSTNISVLNLSQTNIEEFPSNLHLKNLVKFSISKEESDVKQWEGEKPLTPFLAMMLSPTLTSLHLENLPSLVELPSSFQNLNQLKRLFIVRCINLETLPTGINLQSLDSLSFKGCSRLRSFPEISTNISVLYLDETAIEDVPWWIEKFSNLTELSMHSCSRLKWVFLHMSKLKHLKEALFPNCGKLTRVELSGYPSGMEVMKADNIDTASSSLPKVVLSFLDCFNLDPETVLHHQESIIFNYMLFTGKEEVPSYFTYRTTGSSSLTIPLLHVHLSQPFFRFRIGALVKNKEMPGIEVKCEFKDRFGNNFDYYIYFGVHNHRYYKEDGYNIAILDCRIPLNEDNAALAQRNYYDHVDIKIEQLYETYSDIEQWGIRLLEDCSSAETRLDNYSNSTLPHVSEAEEGNIGYTPLQGLVNEIEHSEEPGDINVETERSTKRMR |
| superfamily: SSF52540 | 65-441 | SSF52540 | SRIAVVVFSINYASSSWCLNELLEIVNCNDKIVIPVFYHVDPSQVRHQIGDFGKIFENTCKRQTDEEVKNQWKKALTLVANMLGFDSAKWNDEAKMIEEIANDVLGKLLLTTPKDSEELVGIEDHIAEMSLLLQLESEEVRMVGISGSSGIGKTTIARALFKRLSRHFQGSTFIDRAFVSNSRNIYSGANPDDPNMKLQLQGHFLSEILGKKDIKIDDPAALEERLKHQKVLIIIDDLDDIMVLDTLVGQTQWFGYGSRIIVVTNDKHFLTAHGIDHIYEVSFPTDVHAYQMLCQSAFKQNYAPKGFEDLVVDVVRHAGSFPLGLNLLGKYLRRRDMEYWMDMLPRLENGLRIDGKIEKILRISYDGLESEDQEIFR |
| HMMPfam: PF00931 IPR002182
|
187-454 | NB-ARC,NBS NB-ARC
|
EDHIAEMSLLLQLESEEVRMVGISGSSGIGKTTIARALFKRLSRHFQGSTFIDRAFVSNSRNIYSGANPDDPNMKLQLQGHFLSEILGKKDIKIDDPAALEERLKHQKVLIIIDDLDDIMVLDTLVGQTQWFGYGSRIIVVTNDKHFLTAHGIDHIYEVSFPTDVHAYQMLCQSAFKQNYAPKGFEDLVVDVVRHAGSFPLGLNLLGKYLRRRDMEYWMDMLPRLENGLRIDGKIEKILRISYDGLESEDQEIFRHIACLFNHMEVTT |
| Gene3D: G3DSA:3.40.50.300 | 199-215 | G3DSA:3.40.50.300 | LESEEVRMVGISGSSGI |
| HMMSmart: SM00382 IPR003593
|
203-349 | AAA,NBS AAA+ ATPase domain
|
EVRMVGISGSSGIGKTTIARALFKRLSRHFQGSTFIDRAFVSNSRNIYSGANPDDPNMKLQLQGHFLSEILGKKDIKIDDPAALEERLKHQKVLIIIDDLDDIMVLDTLVGQTQWFGYGSRIIVVTNDKHFLTAHGIDHIYEVSFPT |
| FPrintScan: PR00364 IPR000767
|
206-221 | DISEASERSIST Disease resistance protein
|
MVGISGSSGIGKTTIA |
| Gene3D: G3DSA:3.40.50.300 | 216-257 | G3DSA:3.40.50.300 | GKTTIARALFKRLSRHFQGSTFIDRAFVSNSRNIYSGANPDD |
| FPrintScan: PR00364 IPR000767
|
289-303 | DISEASERSIST Disease resistance protein
|
RLKHQKVLIIIDDLD |
| Gene3D: G3DSA:3.40.50.300 | 294-358 | G3DSA:3.40.50.300 | KVLIIIDDLDDIMVLDTLVGQTQWFGYGSRIIVVTNDKHFLTAHGIDHIYEVSFPTDVHAYQMLC |
| FPrintScan: PR00364 IPR000767
|
382-396 | DISEASERSIST Disease resistance protein
|
AGSFPLGLNLLGKYL |
| superfamily: SSF46785 | 419-523 | SSF46785 | GKIEKILRISYDGLESEDQEIFRHIACLFNHMEVTTIKSLLADSDVSFALENLADKSLIHVRQGYVVMHRSLQEMGRKIVRIQSIDKPGEREFLVDPNDIHDILN |
| Gene3D: G3DSA:3.40.50.300 | 468-491 | G3DSA:3.40.50.300 | LENLADKSLIHVRQGYVVMHRSLQ |
| superfamily: SSF52058 | 534-923 | SSF52058,LRR | ISLDTRNIRELDVHQRAFKGMSNLRFLEIKNFRLKEDSLHLPPSFDYLPRTLKLLSWSKFPMRCMPFDFRPENLVKLEMKYSKLHKLWEGDVPLTCLKEMDLYASSNLKVIPDLSKATNLEILNLQFCLSLVELPSSIRNLNKLLNLDMLDCKSLKILPTGFNLKSLDRLNFSHCSKLKTFPKFSTNISVLNLSQTNIEEFPSNLHLKNLVKFSISKEESDVKQWEGEKPLTPFLAMMLSPTLTSLHLENLPSLVELPSSFQNLNQLKRLFIVRCINLETLPTGINLQSLDSLSFKGCSRLRSFPEISTNISVLYLDETAIEDVPWWIEKFSNLTELSMHSCSRLKWVFLHMSKLKHLKEALFPNCGKLTRVELSGYPSGMEVMKADNID |
| Gene3D: G3DSA:3.80.10.10 | 536-750 | G3DSA:3.80.10.10 | LDTRNIRELDVHQRAFKGMSNLRFLEIKNFRLKEDSLHLPPSFDYLPRTLKLLSWSKFPMRCMPFDFRPENLVKLEMKYSKLHKLWEGDVPLTCLKEMDLYASSNLKVIPDLSKATNLEILNLQFCLSLVELPSSIRNLNKLLNLDMLDCKSLKILPTGFNLKSLDRLNFSHCSKLKTFPKFSTNISVLNLSQTNIEEFPSNLHLKNLVKFSISK |
| HMMPfam: PF07725 IPR011713
|
606-624 | LRR_3 Leucine-rich repeat 3
|
NLVKLEMKYSKLHKLWEGD |
| FPrintScan: PR00364 IPR000767
|
672-688 | DISEASERSIST Disease resistance protein
|
RNLNKLLNLDMLDCKSL |
| Gene3D: G3DSA:3.80.10.10 | 772-919 | G3DSA:3.80.10.10 | LSPTLTSLHLENLPSLVELPSSFQNLNQLKRLFIVRCINLETLPTGINLQSLDSLSFKGCSRLRSFPEISTNISVLYLDETAIEDVPWWIEKFSNLTELSMHSCSRLKWVFLHMSKLKHLKEALFPNCGKLTRVELSGYPSGMEVMKA |
Diseases
| Disease | Pathogen | Avirulence gene |
|---|---|---|
| White rust | Albugo candida |
List of References
Mohammad H Borhan, Eric B Holub, Jim L Beynon, Kevin Rozwadowski, S Roger Rimmer
The arabidopsis TIR-NB-LRR gene RAC1 confers resistance to Albugo candida (white rust) and is dependent on EDS1 but not PAD4.
Mol. Plant Microbe Interact.: 2004, 17(7);711-9
PubMed:15242165
WorldCat.org
DOI
(P p)
List of Contributions
There has not been any contribution yet.
